Nº 03.8Hormone-related conditions
Insomnia doubles or triples during perimenopause and andropause. We treat the hormonal roots of broken sleep — cortisol, progesterone, melatonin — instead of reaching first for sedatives.
Presentation6 signs
A constellation, not a disease.
HHHC · clinical index
The pathway
Stage · 01
Consult
60-minute in-person assessment with your doctor.
Stage · 02
Test
Full hormone panel, thyroid, metabolic markers.
Stage · 03
Protocol
Bioidentical prescription tuned to your results.
Stage · 04
Follow up
Monitored adjustments as your body responds.
Why Hormones Matter for Sleep
Sleep is profoundly influenced by hormones. Progesterone promotes sleep through its metabolite allopregnanolone, which is a potent GABA-A receptor agonist — essentially your body's natural sedative. When progesterone declines in perimenopause, this GABA-ergic sleep support is lost.
Cortisol follows a strict circadian rhythm — high in the morning, low at night. Chronic stress can invert this pattern, leaving you wired at bedtime and exhausted in the morning. Oestrogen decline causes thermoregulatory instability (night sweats) that fragments sleep architecture. Melatonin production declines significantly with age.
Rather than prescribing sedatives that mask the problem and carry dependence risk, we map your hormonal sleep drivers and correct them — restoring natural sleep architecture from the inside out.
Recognising Hormonal Sleep Disruption
Sleep problems with hormonal patterns require different treatment than primary insomnia.
Evidence-Based Sleep Restoration
Hormonal approaches to restore natural sleep architecture.
100-200mg at bedtime — hepatic conversion to allopregnanolone provides GABA-A receptor-mediated sedation. Improves sleep onset and maintenance without morning hangover when dosed correctly.
Immediate-release (0.5-2mg) for sleep onset; prolonged-release (2-4mg) for sleep maintenance. Timing 30-60 min before bed is critical. No tolerance or dependence.
4-point salivary cortisol mapping to identify elevated evening cortisol. Targeted interventions including phosphatidylserine, magnesium glycinate, and sleep hygiene strategies.
Transdermal oestrogen to address night sweats and thermoregulatory disruption that fragments sleep. Preferred route for safety in long-term use.
Learn more about our comprehensive approach to hormone-driven conditions.
Next step
Book a consultation to investigate the hormonal drivers of your insomnia.
